Big Mouth Babes

The philtrum is the vertical groove in the upper lip, formed where the nasomedial and maxillary processes meet during embryo development. When these processes fail to fuse fully, a hare lip and/or cleft palate can result. This can result in the encouraging process of the release of metabolic wastes.
The nasolabial folds are the deep creases of tissue that extend from the nose to the sides of the mouth. One of the first signs of age on the human face is the increase in prominence of the nasolabial folds.