Native American Girl

Chicken pox and measles, although by this time endemic and rarely fatal among Europeans (long after being introduced from Asia), often proved deadly to Native Americans. Smallpox proved particularly fatal to Native American populations. Epidemics often immediately followed European exploration and sometimes destroyed entire village populations. While precise figures are difficult to determine, some historians estimate that at least 30% (and sometimes 50% to 70%) of some Native populations died after first contact due to Eurasian smallpox. One element of the Columbian exchange suggests explorers from the Christopher Columbus expedition contracted syphilis from indigenous peoples and carried it back to Europe, where it spread widely. Other researchers believe that the disease existed in Europe and Asia before Columbus and his men returned from exposure to indigenous peoples of the Americas, but that they brought back a more virulent form.
In 1618–1619, smallpox killed 90% of the Native Americans in the area of the Massachusetts Bay. Historians believe many Mohawk in present-day New York became infected after contact with children of Dutch traders in Albany in 1634. The disease swept through Mohawk villages, reaching the Onondaga at Lake Ontario by 1636, and the lands of the western Iroquois by 1679, as it was carried by Mohawk and other Native Americans who traveled the trading routes. The high rate of fatalities caused breakdowns in Native American societies and disrupted generational exchanges of culture.
Between 1754 and 1763, many Native American tribes were involved in the French and Indian War/Seven Years War. Those involved in the fur trade in the northern areas tended to ally with French forces against British colonial militias. Native Americans fought on both sides of the conflict. The greater number of tribes fought with the French in the hopes of checking British expansion. The British had made fewer allies, but it was joined by some tribes that wanted to prove assimilation and loyalty in support of treaties to preserve their territories. They were often disappointed when such treaties were later overturned. The tribes had their own purposes, using their alliances with the European powers to battle traditional Native enemies.
After European explorers reached the West Coast in the 1770s, smallpox rapidly killed at least 30% of Northwest Coast Native Americans. For the next 80 to 100 years, smallpox and other diseases devastated native populations in the region. Puget Sound area populations, once estimated as high as 37,000 people, were reduced to only 9,000 survivors by the time settlers arrived en masse in the mid-19th century. The e Spanish missions in California did not significantly affect the population of Native Americans, but the numbers of the latter decreased rapidly after California ceased to be a Spanish colony, especially during the second half of the 19th century and the beginning of the 20th.