Pug In Costume

An investigative documentary carried out by the BBC found significant inbreeding between pedigree dogs, with a study by Imperial College, London, showing that the 10,000 pugs in the UK are so inbred that their gene pool is the equivalent of only 50 individuals
Serious issues
Pugs can suffer from necrotizing meningoencephalitis (NME), also known as pug dog encephalitis (PDE), an inflammation of the brain and meninges, that also occurs in other small-breed dogs, such as the Maltese and Chihuahua. There is no known cause or cure for NME, although it is believed to be an inherited disease. All dogs usually die or are euthanised within a few months after the onset of clinical signs, which usually occurs anywhere from 6 months to 7 years of age.