Space Shuttle Atlantis

22 - 8 September 2000 - STS-106 - 39B - KSC - 11 days, 19 hours, 12 minutes, 15 seconds - 4,919,243 miles (7,916,754 km) - International Space Station resupply mission. STS-106 utilized the SPACEHAB Double Module and the Integrated Cargo Carrier (ICC) to bring supplies to the ISS. The mission also included two spacewalks.
23 - 7 February 2001 - STS-98 - 39A - Edwards AFB - 12 days, 21 hours, 21 minutes - 5,369,576 miles (8,641,495 km) - International Space Station assembly mission (carried and assembled the Destiny Laboratory Module). Three spacewalks including the 100th in the U.S. manned spaceflight program were conducted to complete its assembly.
24 - 12 July 2001 - STS-104 - 39B - KSC - 12 days, 18 hours, 36 minutes, 39 seconds - 5,309,429 miles (8,544,698 km) - International Space Station assembly mission (carried and assembled the Quest Joint Airlock). Astronauts Michael Gernhardt and James Reilly conducted three space walks while Atlantis was docked to the ISS. STS-104 was the first shuttle mission to fly with a "Block II" SSME.
25 - 8 April 2002 - STS-110 - 39B - KSC - 10 days, 19 hours, 43 minutes, 48 seconds - 4,525,299 miles (7,282,763 km) - International Space Station assembly mission (carried and assembled the S0 truss segment) which forms the backbone of the truss structure on the ISS. STS-110 also delivered the Mobile Transporter (MT). Four spacewalks were also conducted in support of ISS construction.